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Dear Scientist,

With your published research papers, you have helped chemical biology continue to flourish. Today, we have set up for you free access to the 25 most accessed articles in ChemBioChem over the last 12 months. Within this list, you will notice a good spread of topics–an indication that our manuscripts are read by a broad section of the chemical and life science communities.

We would love to welcome you amongst our authors. You can get an impression of the high quality of ChemBioChem by reading the articles below–we hope to see your next good manuscript on one of our future lists!


Best wishes,

Meghan Campbell

Meghan Campbell
Deputy Editor
ChemBioChem


25 Most Accessed Articles from ChemBioChem:

Free Fluorine in Medicinal Chemistry
Hans-Joachim Böhm, David Banner, Stefanie Bendels, Manfred Kansy, et al.

Free Giant Vesicles: Preparations and Applications
Peter Walde, Katia Cosentino, Helen Engel, Pasquale Stano

Free Using a Fragment-Based Approach To Target Protein–Protein Interactions
Duncan E. Scott, Matthias T. Ehebauer, Tara Pukala, et al.

Free Azide: A Unique Dipole for Metal-Free Bioorthogonal Ligations
Marjoke F. Debets, Christianus W. J. van der Doelen, Floris P. J. T. Rutjes,
Floris L. van Delft


Free Drug Design Strategies for Targeting G-Protein-Coupled Receptors
Thomas Klabunde, Gerhard Hessler

Free Design of Gold Nanoparticle-Based Colorimetric Biosensing Assays
Weian Zhao, Michael A. Brook, Yingfu Li

Free Development of SNAP-Tag Fluorogenic Probes for Wash-Free Fluorescence Imaging
Xiaoli Sun, Aihua Zhang, Brenda Baker, et al.

Free Structure and Function of Mammalian DNA Methyltransferases
Renata Zofia Jurkowska, Tomasz Piotr Jurkowski, Albert Jeltsch

Free Imaging the Sialome during Zebrafish Development with Copper-Free Click Chemistry
Karen W. Dehnert, Jeremy M. Baskin, Scott T. Laughlin, et al.

Free Rapid Flow-Based Peptide Synthesis
Mark D. Simon, Patrick L. Heider, Andrea Adamo, et al.

Free S-Adenosyl-Methionine-Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications
Anna-Winona Struck, Mark L. Thompson, Lu Shin Wong, Jason Micklefield

Free Aqueous Oxidative Heck Reaction as a Protein-Labeling Strategy
Maria Eleni Ourailidou, Jan-Ytzen van der Meer, Bert-Jan Baas, et al.

Free Fluorescent Amino Acids: Modular Building Blocks for the Assembly of New Tools for Chemical Biology
Andrew T. Krueger, Barbara Imperiali

Free Click Chemistry for Rapid Labeling and Ligation of RNA
Eduardo Paredes, Subha R. Das

Free A Label-Free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence
Dorothea Pinotsi, Alexander K. Buell, Christopher M. Dobson,
Gabriele S. Kaminski Schierle, Clemens F. Kaminski


Free Fluorescent Probes for G-Quadruplex Structures
Balayeshwanth R. Vummidi, Jawad Alzeer, Nathan W. Luedtke

Free Molecular Assembly of an Aptamer–Drug Conjugate for Targeted Drug Delivery to Tumor Cells
Yu-Fen Huang, Dihua Shangguan, Haipeng Liu, Joseph A. Phillips,
Xiaoling Zhang, Yan Chen, Weihong Tan


Free Probing Protein–Protein Interactions with a Genetically Encoded Photo-crosslinking Amino Acid
Hui-wang Ai, Weijun Shen, Amit Sagi, Peng R. Chen, Peter G. Schultz

Free Inhibition of Lipopolysaccharide Transport to the Outer Membrane in Pseudomonas aeruginosa by Peptidomimetic Antibiotics
Martina Werneburg, Katja Zerbe, Mario Juhas, et al.

Free Molecular Diversity Sculpted by Fungal PKS–NRPS Hybrids
Daniela Boettger, Christian Hertweck

Free Quantitative Proteomics for Epigenetics
H. Christian Eberl, Matthias Mann, Michiel Vermeulen

Free FRET-Capture: A Sensitive Method for the Detection of Dynamic Protein Interactions
Elke Socher, Barbara Imperiali

Free Chemoenzymatic Bio-orthogonal Chemistry for Site-Specific Double Modification of Recombinant Thrombomodulin
Rui Jiang, Lin Wang, Jacob Weingart, Xue-Long Sun

Free Small-Molecule Proteomimetic Inhibitors of the HIF-1α–p300 Protein–Protein Interaction
George M. Burslem, Hannah F. Kyle, Alexander L. Breeze, et al.

Free Ubiquitin-Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes
Annemieke de Jong, Remco Merkx, Ilana Berlin, et al.


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